DOI: 10.1111/ele.12625
Scopus记录号: 2-s2.0-84977138123
论文题名: Allele surfing promotes microbial adaptation from standing variation
作者: Gralka M. ; Stiewe F. ; Farrell F. ; Möbius W. ; Waclaw B. ; Hallatschek O.
刊名: Ecology Letters
ISSN: 1461023X
EISSN: 1461-0248
出版年: 2016
语种: 英语
英文关键词: Biological invasions
; Dynamics of adaptation
; Eco-evolutionary feedback
; Gene surfing
; Genetic drift
; Range expansions
Scopus关键词: adaptation
; allele
; biological model
; computer simulation
; ecosystem
; evolution
; genetics
; physiology
; Saccharomyces cerevisiae
; Adaptation, Physiological
; Alleles
; Biological Evolution
; Computer Simulation
; Ecosystem
; Models, Biological
; Saccharomyces cerevisiae
英文摘要: The coupling of ecology and evolution during range expansions enables mutations to establish at expanding range margins and reach high frequencies. This phenomenon, called allele surfing, is thought to have caused revolutions in the gene pool of many species, most evidently in microbial communities. It has remained unclear, however, under which conditions allele surfing promotes or hinders adaptation. Here, using microbial experiments and simulations, we show that, starting with standing adaptive variation, range expansions generate a larger increase in mean fitness than spatially uniform population expansions. The adaptation gain results from 'soft' selective sweeps emerging from surfing beneficial mutations. The rate of these surfing events is shown to sensitively depend on the strength of genetic drift, which varies among strains and environmental conditions. More generally, allele surfing promotes the rate of adaptation per biomass produced, which could help developing biofilms and other resource-limited populations to cope with environmental challenges. © 2016 John Wiley & Sons Ltd/CNRS. Citation statistics:
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/107828
Appears in Collections: 气候减缓与适应
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作者单位: Departments of Physics and Integrative Biology University of California Berkeley 94720CA USA; Biophysics and Evolutionary Dynamics Group Max Planck Institute for Dynamics and Self-Organization 37077 Göttingen Germany; SUPA School of Physics and Astronomy The University of Edinburgh Mayfield Road Edinburgh EH9 3JZ UK; Centre for Synthetic and Systems Biology The University of Edinburgh Edinburgh UK
Recommended Citation:
Gralka M.,Stiewe F.,Farrell F.,et al. Allele surfing promotes microbial adaptation from standing variation[J]. Ecology Letters,2016-01-01