DOI: 10.1016/j.jcou.2018.09.022
Scopus记录号: 2-s2.0-85054500014
论文题名: Supercritical extraction strategies using CO2 and ethanol to obtain cannabinoid compounds from Cannabis hybrid flowers
作者: Grijó D.R. ; Vieitez Osorio I.A. ; Cardozo-Filho L.
刊名: Journal of CO2 Utilization
ISSN: 22129820
出版年: 2018
卷: 28 起始页码: 174
结束页码: 180
语种: 英语
英文关键词: Cannabinoid
; Cannabis
; Decarboxylation
; Supercritical extraction
; Winterization
Scopus关键词: Carbon dioxide
; Carboxylation
; Chemical analysis
; Essential oils
; Ethanol
; Supercritical fluid extraction
; Cannabinoid
; Cannabis
; Decarboxylation
; Supercritical extraction
; Winterization
; Organic solvents
英文摘要: The genus Cannabis contains specific substances called cannabinoids that are found in high concentrations in the flowers of non-pollinated female plants. Cannabidiol (CBD) and Δ9-tetrahydrocannabinol (Δ9-THC) are the two main bioactive substances in this group with medicinal potential. However, these substances are found in low concentrations in fresh flowers. The decarboxylation technique can be applied to fresh flowers to promote an increase in the levels of these substances. Extracts with high levels of cannabinoids and without organic solvent residues have high medicinal and cosmetic potential. The purpose of this work was to present the results of cannabinoid extraction using pressurized fluids from two varieties of flowers of the genus Cannabis. The extractions were conducted using pure supercritical carbon dioxide (scCO2) and with ethanol as a co-solvent, comparing the use of decarboxylation and winterization techniques. The chemical profiles of cannabinoids (CBD, Δ9-THC and cannabinol (CBN)) and the essential oils in the extracts and in fresh flowers were analyzed using different chromatographic techniques. The decarboxylation technique employed maximized the levels of the cannabinoids of interest. The Sovová model used in the adjustment of the experimental kinetic extraction curves was adequate and satisfactory. © 2018 Elsevier Ltd. All rights reserved. Citation statistics:
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/111769
Appears in Collections: 气候减缓与适应
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作者单位: Department of Chemical Engineering, Universidade Estadual de Maringá, Maringá, PR, Brazil; Departmento de Ciencia y Tecnología de Alimentos, Universidad de la República, Montevideo, Uruguay; Center for Research, Centro Universitário da Fundação de Ensino Octávio Bastos (UNIFEOB), São João da Boa Vista, SP, Brazil
Recommended Citation:
Grijó D.R.,Vieitez Osorio I.A.,Cardozo-Filho L.. Supercritical extraction strategies using CO2 and ethanol to obtain cannabinoid compounds from Cannabis hybrid flowers[J]. Journal of CO2 Utilization,2018-01-01,28