DOI: 10.1016/j.quascirev.2018.04.033
Scopus记录号: 2-s2.0-85046680199
论文题名: Palaeoproteomics for human evolution studies
作者: Welker F.
刊名: Quaternary Science Reviews
ISSN: 2773791
出版年: 2018
卷: 190 起始页码: 137
结束页码: 147
语种: 英语
英文关键词: Ancient proteins
; Hominin phylogenetics
; Human evolution
; Pleistocene
; Protein degradation
; ZooMS
Scopus关键词: Biology
; DNA
; Gene encoding
; Mass spectrometry
; Ancient proteins
; Human evolution
; Phylogenetics
; Pleistocene
; Protein degradation
; ZooMS
; Proteins
; DNA
; evolutionary biology
; fossil
; Holocene
; hominid
; human evolution
; phylogenetics
; phylogeny
; Pleistocene
; protein
; proteomics
; Europe
英文摘要: The commonplace sequencing of Neanderthal, Denisovan and ancient modern human DNA continues to revolutionize our understanding of hominin phylogeny and interaction(s). The challenge with older fossils is that the progressive fragmentation of DNA even under optimal conditions, a function of time and temperature, results in ever shorter fragments of DNA. This process continues until no DNA can be sequenced or reliably aligned. Ancient proteins ultimately suffer a similar fate, but are a potential alternative source of biomolecular sequence data to investigate hominin phylogeny given their slower rate of fragmentation. In addition, ancient proteins have been proposed to potentially provide insights into in vivo biological processes and can be used to provide additional ecological information through large scale ZooMS (Zooarchaeology by Mass Spectrometry) screening of unidentifiable bone fragments. However, as initially with ancient DNA, most ancient protein research has focused on Late Pleistocene or Holocene samples from Europe. In addition, only a limited number of studies on hominin remains have been published. Here, an updated review on ancient protein analysis in human evolutionary contexts is given, including the identification of specific knowledge gaps and existing analytical limits, as well as potential avenues to overcome these. © 2018 Elsevier Ltd Citation statistics:
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/112189
Appears in Collections: 气候减缓与适应
There are no files associated with this item.
作者单位: Department of Human Evolution, Max-Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, Leipzig, 04103, Germany; Natural History Museum of Denmark, University of Copenhagen, Øster Voldgade 5-7, Copenhagen, 1350, Denmark
Recommended Citation:
Welker F.. Palaeoproteomics for human evolution studies[J]. Quaternary Science Reviews,2018-01-01,190