DOI: 10.1016/j.watres.2018.05.032
Scopus记录号: 2-s2.0-85049320220
论文题名: Why are organic micropollutants not fully biotransformed? A mechanistic modelling approach to anaerobic systems
作者: Gonzalez-Gil L. ; Mauricio-Iglesias M. ; Carballa M. ; Lema J.M.
刊名: Water Research
ISSN: 431354
出版年: 2018
卷: 142 起始页码: 115
结束页码: 128
语种: 英语
英文关键词: Bioavailability
; Biotransformation mechanism
; Incomplete removal
; Mathematical modelling
; Parameter estimation
; Pharmaceuticals
Scopus关键词: Batch reactors
; Biochemistry
; Biological water treatment
; Drug products
; Kinetics
; Mathematical models
; Parameter estimation
; Phase transitions
; Thermodynamics
; Wastewater treatment
; Bioavailability
; Biological reaction
; Chemical equilibriums
; Continuous reactors
; Estimated parameter
; Michaelis-Menten kinetic
; Organic micro-pollutants
; Transformation products
; Bioconversion
; anoxic conditions
; bioassay
; bioavailability
; biotransformation
; drug
; experimental study
; kinetics
; numerical model
; organic pollutant
; pollutant removal
; prediction
; sludge
; wastewater treatment
; anaerobic digestion
; Article
; assay
; batch assay
; bioavailability
; biomass
; biotransformation
; calibration
; controlled study
; enzyme inhibition
; hydrophobicity
; kinetics
; mathematical model
; mechanistic model
; methanogenesis
; methanogenic biomass
; Michaelis Menten kinetics
; organic micropollutant
; pollutant
; priority journal
; sludge
; solid
; thermodynamics
英文摘要: Biotransformation of most organic micropollutants (OMPs) during wastewater treatment is not complete and an unexplained steady decrease of the biotransformation rate with time is reported for many OMPs in different biological processes. To minimize and accurately predict the emission of OMPs into the environment, the mechanisms and limitations behind their biotransformations should be clarified. Aiming to achieve this objective, the present study follows a mechanistic modelling approach, based on the formulation of four models according to different biotransformation hypotheses: Michaelis-Menten kinetics, chemical equilibrium between the parent compound and the transformation product (TP), enzymatic inhibition by the TP, and a limited compound bioavailability due to its sequestration in the solid phase. These models were calibrated and validated with kinetic experiments performed in two different anaerobic systems: continuous reactors enriched with methanogenic biomass and batch assays with anaerobic sludge. Model selection was conducted according to model suitability criteria (goodness of fitting the experimental data, confidence of the estimated parameters, and model parsimony) but also considering mechanistic evidences. The findings suggest that reversibility of the biological reactions and/or sequestration of compounds are likely the causes preventing the complete biotransformation of OMPs, and biotransformation is probably limited by thermodynamics rather than by kinetics. Taking into account its simplicity and broader applicability spectrum, the reversible biotransformation is the proposed model to explain the incomplete biotransformation of OMPs. © 2018 Elsevier Ltd Citation statistics:
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/112633
Appears in Collections: 气候减缓与适应
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作者单位: Department of Chemical Engineering, School of Engineering, Universidade de Santiago de Compostela, Rúa Lope Gómez de Marzoa, Santiago de Compostela, E-15782, Spain
Recommended Citation:
Gonzalez-Gil L.,Mauricio-Iglesias M.,Carballa M.,et al. Why are organic micropollutants not fully biotransformed? A mechanistic modelling approach to anaerobic systems[J]. Water Research,2018-01-01,142