DOI: 10.1016/j.watres.2018.03.056
Scopus记录号: 2-s2.0-85047407163
论文题名: Analysis of endocrine activity in drinking water, surface water and treated wastewater from six countries
作者: Leusch F.D.L. ; Neale P.A. ; Arnal C. ; Aneck-Hahn N.H. ; Balaguer P. ; Bruchet A. ; Escher B.I. ; Esperanza M. ; Grimaldi M. ; Leroy G. ; Scheurer M. ; Schlichting R. ; Schriks M. ; Hebert A.
刊名: Water Research
ISSN: 431354
出版年: 2018
卷: 139 起始页码: 10
结束页码: 18
语种: 英语
英文关键词: Bioassay
; Effect-based trigger value
; Endocrine activity
; Environmental waters
; In vitro
Scopus关键词: Aquatic ecosystems
; Bioassay
; Health
; Health risks
; Indicators (chemical)
; Industrial chemicals
; Isomers
; Potable water
; Steroid hormones
; Wastewater treatment
; Water treatment
; Aquatic environments
; Chemical concentrations
; Drinking water samples
; Effect-based trigger value
; Endocrine activity
; Environmental water
; In-vitro
; Limit of quantifications
; Surface waters
; drinking water
; estrogen
; glucocorticoid
; industrial chemical
; mineralocorticoid
; pesticide
; surface water
; drinking water
; drug
; endocrine disruptor
; glucocorticoid
; pesticide
; retinoid X receptor
; steroid receptor
; thyroid hormone receptor
; bioassay
; chemical analysis
; chemical pollutant
; drinking water
; endocrine system
; laboratory method
; surface water
; wastewater
; aquatic environment
; Article
; Australia
; bioassay
; chemical analysis
; ecosystem
; ecosystem health
; electrospray mass spectrometry
; endocrine function
; estrogen activity
; France
; Germany
; health hazard
; human
; in vitro study
; limit of quantitation
; liquid chromatography-mass spectrometry
; Netherlands
; priority journal
; risk assessment
; South Africa
; Spain
; waste water
; waste water management
; water analysis
; water quality
; water sampling
; analysis
; bioassay
; environmental monitoring
; metabolism
; waste water
; water pollutant
; Australia
; France
; Germany
; Netherlands
; South Africa
; Spain
; Biological Assay
; Drinking Water
; Ecosystem
; Endocrine Disruptors
; Environmental Monitoring
; Glucocorticoids
; Pesticides
; Pharmaceutical Preparations
; Receptors, Steroid
; Receptors, Thyroid Hormone
; Retinoid X Receptors
; Waste Water
; Water Pollutants, Chemical
英文摘要: The aquatic environment can contain numerous micropollutants and there are concerns about endocrine activity in environmental waters and the potential impacts on human and ecosystem health. In this study a complementary chemical analysis and in vitro bioassay approach was applied to evaluate endocrine activity in treated wastewater, surface water and drinking water samples from six countries (Germany, Australia, France, South Africa, the Netherlands and Spain). The bioassay test battery included assays indicative of seven endocrine pathways, while 58 different chemicals, including pesticides, pharmaceuticals and industrial compounds, were analysed by targeted chemical analysis. Endocrine activity was below the limit of quantification for most water samples, with only two of six treated wastewater samples and two of six surface water samples exhibiting estrogenic, glucocorticoid, progestagenic and/or anti-mineralocorticoid activity above the limit of quantification. Based on available effect-based trigger values (EBT) for estrogenic and glucocorticoid activity, some of the wastewater and surface water samples were found to exceed the EBT, suggesting these environmental waters may pose a potential risk to ecosystem health. In contrast, the lack of bioassay activity and low detected chemical concentrations in the drinking water samples do not suggest a risk to human endocrine health, with all samples below the relevant EBTs. © 2018 Elsevier Ltd Citation statistics:
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/112758
Appears in Collections: 气候减缓与适应
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作者单位: Australian Rivers Institute, School of Environment and Science, Griffith University, Southport QLD4222, Australia; Veolia Research & Innovation, Maisons-Laffitte, 78600, France; Environmental Chemical Pollution and Health Research Unit, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa; Institut de Recherche en Cancérologie de Montpellier, INSERM/Université de Montpellier, Montpellier, 34298, France; CIRSEE (Centre International de Recherche Sur l'Eau et l'Environnement) – Suez Environnement, Le Pecq, 78230, France; UFZ – Helmholtz Centre for Environmental Research, Leipzig, 04318, Germany; Eberhard Karls University Tübingen, Environmental Toxicology, Center for Applied Geosciences, Tübingen, 72074, Germany; DVGW – Technologiezentrum Wasser, Karlsruher Str.84, Karlsruhe, 76139, Germany; KWR Watercycle Research Institute, Nieuwegein, PE 3433, Netherlands; Vitens drinking water company, Zwolle, BE 8019, Netherlands
Recommended Citation:
Leusch F.D.L.,Neale P.A.,Arnal C.,et al. Analysis of endocrine activity in drinking water, surface water and treated wastewater from six countries[J]. Water Research,2018-01-01,139