DOI: 10.1016/j.watres.2018.02.040
Scopus记录号: 2-s2.0-85042438349
论文题名: Estrogenic activity and contributing compounds in stagnant water bodies with massive occurrence of phytoplankton
作者: Prochazkova T. ; Sychrova E. ; Vecerkova J. ; Javurkova B. ; Otoupalikova A. ; Pernica M. ; Simek Z. ; Smutna M. ; Lepsova-Skacelova O. ; Hilscherova K.
刊名: Water Research
ISSN: 431354
出版年: 2018
卷: 136 起始页码: 12
结束页码: 21
语种: 英语
英文关键词: Alkylphenols
; Estrogenicity
; Estrogens
; Flavonoids
; Surface water
Scopus关键词: Bioactivity
; Bioassay
; Endocrinology
; Flavonoids
; Hormones
; Phytoplankton
; Reservoirs (water)
; Surface waters
; Alkylphenols
; Estrogenic activities
; Estrogenic compounds
; Estrogenic hormones
; Estrogenicity
; Estrogens
; Phytoplankton abundances
; Quantification limit
; Water pollution
; 16alpha hydroxy 17beta estradiol 2,4 d2
; 17alpha estradiol 2,4,16,16 d4
; 17alpha ethynylestradiol 2,4,16,d4
; 4 octylphenol
; 4 tert octylphenol
; 4,4' isopropylidenediphenol
; alkylphenol
; estradiol
; estriol
; estrogen
; estrone
; ethinylestradiol
; phenol derivative
; phytoestrogen
; unclassified drug
; water
; endocrine disruptor
; estrogen
; fresh water
; Anabaenopsis elenkinii
; Article
; bioassay
; biological activity
; Centrales
; Ceratium hirundinella
; Coelastrum microporum
; Cuspidothrix issatchenkoi
; Cylindrospermopsis raciborskii
; Desmodesmus communis
; Desmodesmus magnus
; Desmodesmus opoliensis
; Desmodesmus subspicatus
; Dinobryon cylindricum
; Dolichospermum crassum
; Dolichospermum curvum
; Dolichospermum macrosporum
; Dolichospermum mucosum
; Dolichospermum planctonicum
; Dolichospermum smithii
; Dolichospermum viguieri
; Komvophoron constrictum
; lake
; limit of quantitation
; liquid chromatography-mass spectrometry
; Microcystis aeruginosa
; Microcystis viridis
; Microcystis wesenbergii
; Oocystis marssonii
; Pediastrum boryanum
; Phacus longicauda
; phytoplankton
; Planctonema lauterbornii
; Planktothrix agardhii
; Plantothrix agardhii
; pond
; priority journal
; Tetraedron minimum
; Trachelomonas hispida
; water analysis
; Woloszynskia
; Woronichinia naegeliana
; analysis
; chemistry
; liquid chromatography
; metabolism
; phytoplankton
; tandem mass spectrometry
; water pollutant
; Chromatography, Liquid
; Endocrine Disruptors
; Estrogens
; Fresh Water
; Phytoplankton
; Tandem Mass Spectrometry
; Water Pollutants, Chemical
英文摘要: Stagnant water bodies have generally received little attention regarding the presence of endocrine disruptive compounds, although they can integrate diverse pollutants from multiple different sources. Many compounds of anthropogenic as well as natural origin can contribute to the overall estrogenicity of surface waters and some of them can exhibit adverse effects on aquatic biota even in very low concentrations. This study focused on freshwater ponds and reservoirs affected by water blooms and determined the estrogenic activity of water by in vitro bioassay as well as concentrations of several important groups of estrogenic compounds (estrogenic hormones, alkylphenols, and phytoestrogens) by LC-MS/MS analyses. Estrogenic hormones were found at concentrations up to 7.1 ng.L−1, similarly to flavonoids, whose concentrations did not exceed 12.5 ng.L−1. Among alkylphenols, only bisphenol A and 4-tert-octylphenol were detected in levels reaching 100 ng.L−1 at maximum. Estrogenic activity of water samples varied from below the quantification limit to 1.95 ng.L−1. There does not seem to be any general causal link of the massive phytoplankton occurrence with the estrogenicity of water or concentration of phytoestrogens, since they showed no direct relationship with the phytoplankton abundance or composition across sites. The contribution of the analysed compounds to the estrogenic activity was calculated in three scenarios. In minimum scenario, just the compounds above quantification limit (LOQ) were taken into account and for most samples, only minor part (<6%) of the biological activity could be explained. In the mean and maximum scenarios, we included also compounds below LOQ into the calculations at the level of LOQ/2 and LOQ, respectively. In these cases, a considerable part of the estrogenic activity could be attributed to the possible presence of steroid estrogens below LOQ. However, for the samples with estrogenic activity greater than 1 ng.L−1, more than 50% of the estrogenic activity remained unexplained even in the maximum scenario. Probably other compounds or possible interactions between individual substances cause the estrogenic activity in these types of water bodies and in this case, the results of LC-MS/MS analyses cannot sufficiently predict the biological effects. A complex approach including bioassays is needed when assessing the estrogenicity of these types of surface waters. © 2018 Elsevier Ltd Citation statistics:
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/112844
Appears in Collections: 气候减缓与适应
There are no files associated with this item.
作者单位: RECETOX – Research Centre for Toxic Compounds in the Environment, Masaryk University, Faculty of Science, Brno, Czech Republic; Department of Botany, University of South Bohemia, Faculty of Science, Ceske Budejovice, Czech Republic
Recommended Citation:
Prochazkova T.,Sychrova E.,Vecerkova J.,et al. Estrogenic activity and contributing compounds in stagnant water bodies with massive occurrence of phytoplankton[J]. Water Research,2018-01-01,136