DOI: 10.1016/j.watres.2019.02.052
Scopus记录号: 2-s2.0-85062423705
论文题名: Innovative drinking water treatment techniques reduce the disinfection-induced oxidative stress and genotoxic activity
作者: Lundqvist J. ; Andersson A. ; Johannisson A. ; Lavonen E. ; Mandava G. ; Kylin H. ; Bastviken D. ; Oskarsson A.
刊名: Water Research
ISSN: 431354
出版年: 2019
卷: 155 起始页码: 182
结束页码: 192
语种: 英语
英文关键词: Disinfection byproducts
; Drinking water
; Genotoxicity
; Nrf2
; Oxidative stress
英文摘要: Disinfection of drinking water using chlorine can lead to the formation of genotoxic by-products when chlorine reacts with natural organic matter (NOM). A vast number of such disinfection by-products (DBPs) have been identified, making it almost impossible to routinely monitor all DBPs with chemical analysis. In this study, a bioanalytical approach was used, measuring oxidative stress (Nrf2 activity), genotoxicity (micronucleus test), and aryl hydrocarbon receptor (AhR) activation to evaluate an innovative water treatment process, including suspended ion exchange, ozonation, in-line coagulation, ceramic microfiltration, and granular activated carbon. Chlorination was performed in laboratory scale after each step in the treatment process in order to investigate the effect of each treatment process to the formation of DBPs. Suspended ion exchange had a high capacity to remove dissolved organic carbon (DOC) and to decrease UV absorbance and Nrf2 activity in non-chlorinated water. High-dose chlorination (10 mg Cl 2 L −1 ) of raw water caused a drastic induction of Nrf2 activity, which was decreased by 70% in water chlorinated after suspended ion exchange. Further reduction of Nrf2 activity following chlorination was achieved by ozonation and the concomitant treatment steps. The ozonation treatment resulted in decreased Nrf2 activity in spite of unchanged DOC levels. However, a strong correlation was found between UV absorbing compounds and Nrf2 activity, demonstrating that Nrf2 inducing DBPs were formed from pre-cursors of a specific NOM fraction, constituted of mainly aromatic compounds. Moreover, high-dose chlorination of raw water induced genotoxicity. In similarity to the DOC levels, UV absorbance and Nrf2 activity, the disinfection-induced genotoxicity was also reduced by each treatment step of the innovative water treatment technique. AhR activity was observed in the water produced by the conventional process and in the raw water, but the activity was clearly decreased by the ozonation step in the innovative water treatment process. © 2019 The Author(s) Citation statistics:
资源类型: 期刊论文
标识符: http://119.78.100.158/handle/2HF3EXSE/121901
Appears in Collections: 气候变化事实与影响
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作者单位: Department of Biomedical Sciences and Veterinary Public Health, Swedish University of Agricultural Sciences, Box 7028, Uppsala, SE-750 07, Sweden; Department of Thematic Studies-Environmental Change, Linköping University, Linköping, SE-581 83, Sweden; Department of Clinical Sciences, Swedish University of Agricultural Sciences, Box 7054, Uppsala, SE-750 07, Sweden; Norrvatten, Box 2093, SolnaSE-169 02, Sweden; Stockholm Vatten och AvfallStockholm 106 36, Sweden; Research Unit: Environmental Sciences and Management, North–West University, Potchefstroom, South Africa
Recommended Citation:
Lundqvist J.,Andersson A.,Johannisson A.,et al. Innovative drinking water treatment techniques reduce the disinfection-induced oxidative stress and genotoxic activity[J]. Water Research,2019-01-01,155