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This study uses both the endogenous switching regression and propensity score matching models to analyze the adoption and impact of improved maize varieties on maize yields in central Cameroon. The results show that (i) education level, agricultural training, proximity to an Institute of Agricultural Research for Development branch and farmers' perceptions of yield and risk of improved maize varieties significantly affect the adoption of improved maize varieties and (ii) the adoption of improved maize varieties enhances maize yields. Therefore, policies designed to stimulate adoption of improved maize varieties should be promoted. Improvement of access to school and agricultural training may serve as good strategies for promoting the adoption of improved maize varieties in Cameroon.