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Plants are particularly sensitive to climate change in alpine ecosystem of the Tibetan Plateau. The various mountain micro-climates provide a natural gradient for space-for-time substitution research that plant responses to climate change. In this study, we surveyed the plant community in term of species composition, diversity and biomass across 189 sites on a hill of the Tibetan Plateau and analysed the individual and integrated effects of soil temperature and moisture on the plant community. The results showed that, at the quadrat scale, there were decrease in richness of 1.08 species for every 1 degrees C increase in soil temperature and 356 species for every 10% decrease in soil moisture. The integrated effects of increasing soil temperature and decreasing moisture are expected to lead to a rapid decrease in species richness. Biomass had no significant correlation with soil temperature but significantly decreased with soil moisture decreasing (p <, 0.01). Biomass would decrease when soil moisture was below 20%, no matter how the change of soil temperature. We also found that gramineae and perennial forbs were sensitive to climate change. With soil temperature increased, the proportion of gramineae increased, whereas the proportion of perennial forbs decreased. The integrated effects of soil temperature increasing and moisture decreasing caused a shift from sedge-controlled to gramineae-controlled communities in alpine meadow. This study not only enhances our understanding of mountain plant community dynamics under climate change, but also predicts the shift of vegetation response to climate change on high-elevation alpine meadow. (C) 2018 Elsevier B.V. All rights reserved.