Chemistry, Multidisciplinary
; Green & Sustainable Science & Technology
WOS研究方向:
Chemistry
; Science & Technology - Other Topics
英文摘要:
Biotechnological processes are typically perceived to be greener than chemical processes. A life cycle assessment (LCA) was performed to compare the chemical and biochemical synthesis of lactones obtained by Baeyer-Villiger oxidation. The LCA is prospective (based on experiments at a small scale with primary data) because the process is at an early stage. The results show that the synthesis route has no significant effect on the climate change impact [(1.65 +/- 0.59)kgCO2 g(product)(-1) vs. (1.64 +/- 0.67)kgCO2 g(product)(-1)]. Key process performance metrics affecting the environmental impact were evaluated by performing a sensitivity analysis. Recycling of solvents and enzyme were shown to provide an advantage to the enzymatic synthesis. Additionally, the climate change impact was decreased by 71% if renewable electricity was used. The study shows that comparative LCAs can be used to usefully support decisions at an early stage of process development.
Delgove, Marie A. F.,Laurent, Achille-B.,Woodley, John M.,et al. A Prospective Life Cycle Assessment (LCA) of Monomer Synthesis: Comparison of Biocatalytic and Oxidative Chemistry[J]. CHEMSUSCHEM,2019-01-01,12(7):1349-1360