MEDAKA FISH
; OXIDATIVE STRESS
; MICROCYSTINS
; FRANCE
; OMICS
; NMR
; EUTROPHICATION
; CYANOTOXINS
; POPULATION
; MECHANISMS
WOS学科分类:
Environmental Sciences
WOS研究方向:
Environmental Sciences & Ecology
英文摘要:
With the increasing impact of the global warming, occurrences of cyanobacterial blooms in aquatic ecosystems are becoming a main worldwide ecological concern. Due to their capacity to produce potential toxic metabolites, interactions between the cyanobacteria, their cyanotoxins and the surrounding freshwater organisms have been investigated during the last past years. Non-targeted metabolomic analyses have the powerful capacity to study simultaneously a high number of metabolites and thus to investigate in depth the molecular signatures between various organisms encountering different environmental scenario, and potentially facing cyanobacterial blooms.
In this way, the liver metabolomes of two fish species (Perm fluviatilis and Lepomis gibbosus) colonizing various peri-urban lakes of the Ile-de-France region displaying high biomass of cyanobacteria, or not, were investigated. The fish metabolome hydrophilic fraction was analyzed by H-1 NMR analysis coupled with Batman peak treatment for the quantification and the annotation attempt of the metabolites. The results suggest that similar metabolome profiles occur in both fish species, for individuals collected from cyanobacterial blooming lakes compared to organism from non-cyanobacterial dominant environments. Overall, such environmental metabolomic pilot study provides new research perspectives in ecology and ecotoxicology fields, and may notably provide new information concerning the cyanobacteria/fish ecotoxicological interactions. (C) 2019 Elsevier Ltd. All rights reserved.
1.Museum Natl Hist Nat, UMR 7245 MNHN CNRS Mol Commun & Adaptat Microorga, 12 Rue Buffon, F-75231 Paris 05, France 2.PSL Res Univ, Dept Analyt Bioanalyt Sci & Miniaturizat LSABM, UMR CNRS ESPCI Paris, CBI 8231,ESPCI Paris, 10 Rue Vauquelin, Paris, France
Recommended Citation:
Sotton, Benoit,Paris, Alain,Le Manach, Severine,et al. Specificity of the metabolic signatures of fish from cyanobacteria rich lakes[J]. CHEMOSPHERE,2019-01-01,226:183-191