By using meteorological date and runoff date of Hami region during recent 30years and Mann-Kendall method,runoff change characteristics and the relationship between runoff and climate were analyzed.The results showed that runoff was mainly concentrate in May and September,runoff reached to peak in July,October to the following in March was relatively small.The interannual runoff change was mainly divided into two situations,for the area which supplied by ice and snow melt water had an increasing trend,with the area which supplied by no ice and snow melt water showed obvious decreasing trend.Analysis showed that the monthly runoff and the temperature of ablation period had obvious index relationship, when the temperature of ablation period was greater than 15℃,runoff was accelerated growth.