For the past two decades the system biology based on high throughput analysis has been developed rapidly, as well as the research fields of omics, which include genomics, transcriptomic and proteomic, metabolic techniques. Plants are subjected to different levels of abiotic stresses throughout the life process, which seriously affect their growth and development. The technology of omic is crucial to the study of mechanism of plants response to abiotic stress. Elevated temperature and drought, the two most simultaneously occurring abiotic factors, are the important characteristics of global climate change. This paper reviews the recent advances in omic analyses in plant response to elevated temperature and drought abiotic stresses, as well as the further research perspective in the field, to provide a reference for the future study of plant responses to elevated temperature and drought stresses.