On 31 March 2014, Climate Change 2014: Impacts, Adaptation, and Vulnerability, the Working Group II contribution to the IPCC Fifth Assessment Report (WGII AR5) was released. This report concluded that climate change had caused an extensive and far-reaching influence on global natural and human systems, including 11 sectors and 9 regions (i.e. all continents, polar regions and small islands). Eight kinds of key risks that span sectors and regions are investigated to threaten the natural and human systems. The human systems have obvious vulnerability and exposure to climate risks, in particularly to the climatic extremes. The climatic resilience of natural system and human society should be enhanced through disaster risk management with core of iterative processes and synergies. Combined with mitigation, and transformations in economy, society, technology, and political decisions and actions, a sustainable social and economic development can enable climate-resilient pathways by effective adaptation.