Extreme drought events on the Qinghai-Tibetan Plateau (QTP) could not only result in hydrological anomalies to the plateau-originated rivers but also involve deep influences on all systems to human beings within the watersheds. However, the spatio-temporal patterns of occurrences of extreme drought events and their linkages to large scale climate circulations and global changes are rarely understood. Few researches are developed related to extreme drought events was due to short meteorological and hydrologic records. In this study, we collected tree-ring samples (Sabina tibetica Kom.) from three sites on the southeast QTP (Maxiu : 31.08°N, 94.58°E ; Reyu :31.16°N, 95.24°E; Lajiu: 30.58°N, 96.18°E). To select climate sensitive trees, old trees with habitats characterized by shallow soil layers and more open canopy covers were preferred during the field sampling. Following the standard dendrochronological methods,we mounted,polished,cross-dated,and measured tree core samples. The successfully cross-dated tree ring width series were then subjected to ARSTAN software to be detrended using spline functions with 50% frequency response cutoff with half of the full length of the tree cores. Tree ring index was calculated as ratios of the raw measurements and the detrending functions for each core. To exclude autocorrelation effects, we derived residuals though fitting an autoregression model for each detrended tree ring index sequence. These residual series were at last averaged using bi-weight robust mean method to develop a chronology for each site (site chronology),as well as for the latter pooled dataset (the regional chronology). Climate data,including monthly mean temperature,monthly mean maximum temperature,monthly mean minimum temperature, monthly total precipitation, and monthly mean relative air humidity, was obtained from the Dingqing Meteorological Station (31.42°N, 95.6°E). Besides, Standardized Precipitation-Evapotranspiration Index (SPEI) with a 12-month time scale was retrieved over the region of 30.5° ~31.5°N, 94.5° ~ 96.5°E. The SPEI data was downloaded from the Royal Netherlands Meteorological Institute website (http: // climexp. knmi. nl/). These climate variables were subsequently correlated with tree-ring chronologies by using correlation functions for the period 1954~2006A.D. We found that tree growth was significantly and positively correlated with mean May-August SPEI. The frequencies of low-growth events were thus analyzed since the 1560A.D. till 2006A.D. to infer regional extreme drought event history. The inferred frequency of severe drought events varied through time during past centuries. Extreme drought events occurred most frequently (6 out of 50 years) during the period 1650A.D.~ 1750A.D. The periods 1600 ~ 1650A.D.,1800 ~1850A.D.,and 1950 ~ 2000A.D. had relatively low incidence of extreme drought events (once for each period). Noticeably, the twentieth century had a below-average frequency of extreme droughts. The Indian summer monsoon is probably the most important climate forcing for the occurrence of the extreme drought events. Moreover, our results suggested that the period with most frequent drought events (1650 ~ 1700A.D.) coincided with the Maunder Minimum, a period of extreme solar inactivity that occurred between 1645A.D. and 1710A.D. It indicates that a possible linkage between regional drought events and solar activities though Asian summer monsoon.