Environmental change caused by climate change and human activities has great influence on the human water system, which has also been a major concern all over the world.In this paper,the research status of the impacts of climate change,human activities,and the combined action on the human water system was analyzed and summarized,and the key problems regarding the current study were proposed from five aspects including impact mechanism,environmental change factors,impact of environment change on human system,comprehensive study on human-water system,and quantitative method for the impact on" integrated system".In order to solve the key problems,future research focus for the study was proposed.In addition,the preliminary research ideas were put forward in order to provide reference for future work.