A plot experiment was carried out to study the effect of drainage measures on CH_4 and N_2O emissions from winter wheat fields in Chaohu experimental station, Anhui Agricultural University in 2012 ~ 2013. The results were as follows. (1) Significant difference (P < 0.05) of CH_4 emission and highly significant difference (P < 0.01) of N_2O emission were observed between different drainage measures. (2) During the whole growth stage of winter wheat, CH_4 and N_2O emissions from winter wheat fields changed remarkably seasonally and were greatly influenced by the difference drainage measures. CS treatments had a stronger CH_4 absorption ability compared with others, increasing by 33% compared with CK and the N_2O emissions of CQ and CS treatments were significantly increased by 90.8% and 104% compared with CK treatments. (3) Considering integratedly the total global warming potential (GWP) of CH_4 and N_2O emissions in wheat- growing season, among all treatments, CS treatment had increased the uptake of CH_4 and the emission of N_2O and CQ treatment also increased the emission of N_2O but had not tremendous influence on CH_4. The GWP of CQ treatment was decreased by 9% and 24% while the production was not decreased; thus, it was an effective strategy for mitigation of CH_4 and N_2O greenhouse effect of non- rice growth season.