【Objective】 The study predicted the future variations of temperature and precipitation under A2 and B2 scenarios (HadCM3) in Hexi corridor. 【Method】 Choosing daily average temperature, daily minimum temperature, daily maximum temperature and daily precipitation of 14 stations as predictands and using atmospheric variables of HadCM3 models and the NCEP reanalysis data as predictorsaims, SDSM was applied to predict the change of temperature and precipitation in future.【Result】 The explained variances of temperature and precipitation in Hexi corridor were 0.54 - 0.85 and 0.09 -0.64,respectively. Daily average temperature, daily minimum temperature, and daily maximum temperature would increase by 4.8,2.4, and 5.4 °C in 2070 - 2099 under A2 scenario,and increase by 3.5,2.0,and 4.0 ℃ under B2 scenario. Annual precipitation would increase by 20.0% in 2070 - 2099 under A2 scenario, and increase by 6.7% under B2 scenario in the western parts of this region, while it would decrease by 22.0% in 2070 - 2099 under A2 scenario and decrease by 15.4% under B2 scenario in the center and eastern of this region. In future,extreme high and low temperatures would increase and the probability of extreme precipitation events would decrease. 【Conclusion】 The simulation of temperature by SDSM was better than precipitation. The daily minimum temperature, daily maximum temperature, and daily average temperature would increase from 2010 - 2039 to 2070 - 2099 under A2 and B2,and the increments of daily maximum temperature and daily average temperature would be larger than that of daily minimum temperature. Daily precipitation would change differently in different areas with increase in the western and decrease in the center and eastern of this region.