Field experimental data of winter wheat and parallel daily meteorological data at four typical stations in Chongqing City were used to calibrate and validate APSIM-wheat model and determine the genetic parameters for 12 varieties of winter wheat. The results showed that there was a good agreement between the simulated and observed growth periods from sowing to emergence,flowering and maturity of wheat. Root mean squared errors (RMSEs) between simulated and observed emergence,flowering and maturity were 0 - 3,1 - 8,and 0-8 d,respectively. Normalized root mean squared errors (NRMSEs) between simulated and observed above-ground biomass for 12 study varieties were less than 30%. NRMSE between simulated and observed yields for 10 varieties out of 12 study varieties were less than 30%. APSIM-wheat model performed well in simulating phenology,aboveground biomass and yield of winter wheat in Chongqing City,which could provide a foundational support for assessing the impact of climate change on wheat production in the study area based on the model.