In this study,we developed a tree-ring width chronology using the Schrenk spruce(Picea schrenkiana Fisch.et Mey)tree-ring samples.The samples was collected from the Sayram Lake Basin in western Tianshan Mountains.The tree-ring width chronology response to climate change was analyzed using monthly precipitation,temperature(average maximum temperature,mean minimum temperature and average temperature), relative humidity,sunshine,snow (snow depth and snow days)from Wenquan meteorological stations.Response function analysis shows that precipitation and moisture conditions are limiting factor for tree radial growth in Sayram Lake basin,there is a best correlation between tree-ring width chronology and precipitation(r=0.63,p<0.001),while precipitation from previous August to current July is a major limiting factor.The precipitation variability in the past several hundred years may be better reconstruction by tree-ring chronology.The spatial correlation analysis showed that the tree-ring width chronology have a good representative to precipitation variability from previous August to current July in Sayram Lake basin even most of the northern Xinjiang and the mountains of Central Asia.