A mesocosm experiment was conducted to study the effect of water table level on greenhouse gas (CO_2, CH_4, N_2O) emissions in alpine wetland on the Qinghai-Tibetan Plateau. Two treatments were adopted; stable water table (SW; about 0 cm or at soil surface) and dynamic water table (DW; 0 cm reducing to 45 cm and returning to 0 cm). The results showed that alpine wetland water table changes had no significant effect on soil dissolved organic carbon (DOC), but promoted transformations of ammonium (NH_4~+-N) and nitrate (NO_3~--N). The cumulative emissions of CO_2 were 235.2 and 209.7 g/m~2 for SW and DW treatment, respectively but were not significantly different. However, there was a significant treatment difference on CH_4 emissions. Cumulative emission of CH_4 for DW (0.86 g/m~2) decreased by 52.18%, compared with SW (1.79 g/m~2). The cumulative emission of N_2O for SW (6.72 mg/m~2) was significantly higher than that for DW (7.36 mg/m~2). There was a positive correlation between CO_2/CH_4 release and soil temperature in the alpine wetland with soil temperatures below about 10 ℃. The drop in the water table increased the sensitivity of CO_2/CH_4 release to soil temperature. Models of the response of CO_2, CH_4 and N_2O emissions to water table changes were different in alpine wetland on the Qinghai-Tibetan Plateau.