Lop Nor area is a research hotspot of arid region because of the abundant geological environment information in the strata around Lop Nor dry lake. According to regional stratigraphic and tectonic information,sequence of tectonic events,the environmental information of lake sediment,the study reconstructed the quaternary environment and climate change quantitatively or semi quantitatively and estimated the trend of geological environment and climate change in the future. The study showed that,three large-scale tectonic activities which in 767 - 531 ka,255 - 158 ka and 43 - 34 ka (middle-late stage of late pleistocene) influenced the modern topography distribution feature,and the ancient lake location changed since the quaternary period. This area is sated erosion platform, and has relatively stable development history,the erosion rate is about 0.09 - 1.2 mm·ka~(-1) through the bedrock erosionflattenedtime and surrounding stone relics denudation rate. Through the above quaternary geological environment evolution and climate change exploration in northwestern margin of the LBP,we conclude preliminarily the tectonic activities control the hydrological distribution of study area,especially the scope of the ancient lake. In general,the climate of Lop Nor area for acidification is likely to continue.