Based on the observed data of Xilinhaote station in Xilinhe River basin and the station of Abaga and Lixi Stations near the river basin in 1960-2010,using the method of Sliding, linear trend,R/S,Mann-Kendall, Pettitt and Morlet analysis,the interannual temperature and rainfall sequence trends,mutation situations, cycles and future trends in the recent 51 years were analyzed. The result indicated that the annual average temperature was rising,and showed a significant upward trend; winter temperature contributed lot to the warmer of the whole year. The annual average temperature abrupt was in 1987,and the temperature averaged from 1987-2010 was more than 1.36 ℃ that higher than that from 1960 to 1986. There were significant cold-warm cyclical changes with 20-32 years periods. The annual average rainfall was decreasing,the decrease of the summer rains contributed greatly to the precipitation throughout the year. The annual average rain abrupt in was in 1987, and the rainfall averaged from 1987-2010 was more than 1.64mm that higher than that from 1960 to1986. There were significantly dry-wet cyclical changes with 20-32 years periods. The whole basin environment presented a " cold wet-warm dry-cold wet-dry wet".