Owing to the massive use of fossil fuels,environmental pollution,global warming,resource scarcity and energy crisis have become important issues of worldwide concern,both in academia and in industry.The development of eco-green renewable biomass resources is the most important concern in recent years.2,5-Furandicarboxylic acid (FDCA)as one of the most valuable bio-based platform chemicals has attracted more and more attention.This review summarizes recent progress in the preparation of FDCA by chemical and biological methods.The applications of FDCA in the synthesis of polyesters,polyamides,metal organic frameworks,medicines and plasticizers are introduced in detail.Perspectives are also given on the potential applications and future researches of FDCA.