The land surface temperature (T_s) plays an important role on the interaction between atmosphere and ground. The ground observational data from Nagqu Station of Plateau Climate and Environment (NaPlaCE) in the Northern Tibetan Plateau from 2001 to 2012 were used to analyze annual and inter - annual changes and the response to climate changes by statistical analysis method. The result shows that the T_s on the Northern Tibetan Plateau presents a rising tendency in recent years, especially in winter. The difference of T_s and air temperature (T_a) has the maximum in spring, and its value is influenced by the underlying surface. The annual and diurnal variation of the T_s and T_a are obvious, and the T_a variation lags behind T_s. The relationship models based on the T_a, wind speed, soil moisture and T_s demonstrate that the error between the estimated and measured value of T_s fluctuates from 0℃ to 2.0 ℃, indicating that T_s and T_a, wind speed, soil moisture are well related to each other. Particularly, the response of T_s to T_a is obvious in all year, the variation of wind speed have a great influence on the changes of T_s in spring and winter, and the relationship between T_s and soil moisture is notable in summer.