In order to explore the control response of temperature enhancement on growth and soil health of Wheat,a two-year small scale experiment were carried out by the method of Open-top chamber (OTC),and the natural growth under the same condition as a control (CK) . The results showed as follows: in the whole wheat's growth stage,the soil temperature for OTC was greater than CK,while the soil humidity was lower than CK. Simulated temperature enhancement increased the soil respiration at wheat's growth stage,which first increased and then decreased,and for OTC,it was higher than CK at the same stage. Soil respiration was significantly exponential correlated with soil temperature (P < 0. 001),and the exponential regression of OTC and CK could explain the variation of soil respiration by 81. 24% and 75. 38%,respectively. Simulated temperature enhancement increased the soil enzyme activities at wheat's growth stage. The soil enzyme activities of OTC and CK first increased and then decreased at the growth stage. There were significantly exponential relationship between soil enzyme activities and soil temperature (P < 0. 001),and the exponential regression of OTC and CK could explain the variation of soil respiration by 87. 26% and 82. 14%, respectively. The content of chlorophyll a and b of OTC and CK first increased and then decreased,while the content of soluble protein,soluble sugar,leaf N and P content increased gradually with OTC > CK at the same stage. At mature stage,the stem diameter,leaf area index,specific leaf weight,R/S,grains per ear and grain weight under OTC were greater than CK. Taken together,simulated temperature enhancement was beneficial to improve the soil health and promote the growth of wheat,which provide the theoretical basis to realize the high yield and good quality of wheat under the background of global climate change.