In the background of the increasing concern for the global warming resulted from the cumulative greenhouse gas release, it is of great significance to study the carbon footprint of vegetable production, which can service as methods for controlling the emission of greenhouse gases and alleviating contradiction between climate change and the sustainable development of vegetable production. Based on the IPCC listed guidelines for national greenhouse gas inventories, and applying the life-cycle assessment method, dynamic assessment, and multiple regression analysis, this paper examined and calculated the carbon footprint in the vegetable industry of Hubei Province from 2003 to 2013. Results showed that 1) the carbon footprint caused by vegetable production in Hubei Province increased by 23.06%, from 116.05*104 tCE in 2003 to 142.81*104 tCE in 2013; 2) in the vegetable production system, the top three sources for carbon footprint of greenhouse gas emission were fertilizer, pesticides, and irrigation electrical energy input, accounting for 58.07%, 18.47%, and 9.03% of the total emission carbon footprint respectively; 3) from 2003 to 2013, the trend of carbon intensity of land use was stabilized at 0.97-1.29 tCE/hm~2, and the unit production carbon intensity was increased from 37.06 kgCE/t to 39.91 kgCE/t, earning carbon intensity was decreased from 0.10 kgCE per yuan to 0.02 kgCE per yuan, and carbon ecological efficiency was reduced from 1.87 to 1.73; and 4) multiple regression analysis showed that there was a significant linear correlation between the carbon footprint of total greenhouse gas emission and the usage of fertilizer, pesticides, and irrigation electrical energy in vegetable production system of Hubei, with the correlation coefficients of 0.571, 0.341 and 0.228, respectively. Based on the analysis results, this paper provides the following suggestions: enhancing scientific application of fertilizers, raising large-scale land operation level, promoting biological prevention, and constructing greenhouse gas release prevention and control system.