Sichuan Province of Cina possesses rich biodiversity and various climate types. The impacts of climate change on species distribution are of increasing concern, study on the distribution and migrating disciplinavian of species in Sichuan Province under the climate change can provide scientific basis for regional biodiversity conservation. In this study, according to simulate the climate change, with a medium emission scenario rcp4.5,we selected 128 representative climate sensitive species, and used the maximum entropy model to predicte the variation characteristics of number and spatial distribution, and recognitedthe migration characteristicsin the next 50 years and 100 in Sichuan Province. The results showed that: Species diversity in Sichuan will increase with migration of species, especially in Western Sichuan Plateau will changed more strongly. As the suitable habitats for specieschanged,it is expected that the suitable habitats of about 58% of species will present a increasing trend, and others 42% will present a declining trend from 2000 to 2100. most species in Sichuan will show horizontal and vertical migration trend with climate changes,about 54% and 60% will migrate to higher latitudes and higher elevations. The areas which from 1 200 ~ 1 800 m and 3 300 ~4 500 m changed more stronglyshould be given priority attention and protection.