On the basis of the meteorological database including monthly cumulative sunshine hours, temperature and precipitation (1971 - 2013) from Qinyang Meteorological Bureau,Henan province,the climatic change characteristics and its effect on the growth and production of the Huai medicine were analyzed by the methods of moving average,M-K mutation test and multiple linear regression. The results showed that the average temperature increased at the average speed of 0.3 ℃ /10 a in the period of the Huai medicine growth. The average temperature increased 0.4 ℃ /10 a and 0.5 ℃ /10 a in winter season and spring season,respectively. Accumulated temperature ≥10℃ presents significantly increasing trend (P < 0.05) and delaying sustained time. The mean annual precipitation decreased slightly. The seasonal distribution of precipitation was corresponding to the water requirement of the Huai medicine in different growth processes,and the frequency of strong precipitation has decreased,which resists the decaying roots or tubers to a certain extent. The cooperative function of the atmospheric temperature and precipitation significantly affects the production of the Huai medicine (P < 0.05) in the growth period and in the inflated period of roots and /or tubers. The atmospheric temperature change comprised a crucial factor on the Huai medicine production in Qinyang County. To ensure the Huai medicine quality,production and the market demand,the responding measures need to be adopted in the Huai medicine origin region with the global warming.