Using main cycle data transformed from Molet continuous complex wavelet(CMOR) we explored Shangri- La's five main climatic and environmental factors'(yearly temperature, precipitation,absolute huidity,relative humidity and frost days)quantitative prediction models, variation trends and multiple relations based on multiple Ordinary Least Squares(OLS)model, multiple Vector Auto-regression(VAR)modeling and Structural Equation Model(SEM). The raw data was from the Shangri- La meteorological station in Yunnan,China from 1958 to 2012. We conclude that in next 50 years,Shangri-La's temperature will increase at a rate of 0.44 ℃/10a,it will rise about 2℃ after 50 years,reaching about 9℃. Shangri-La's precipitation shows periodic oscillation around its mean value,increasing at a rate of 14.7mm/10a. Shangri- La's absolute humidity will increase at a rate of 0.06 mg/L/10a with obvious periodic oscillation. Shangri-La's relative humidity will decrease at a rate of - 0.96 %/10a with periodic oscillation. Shangri- La's yearly frosty days will decrease at a rate of - 2.8 d/10a with periodic oscillation Shangri- La's temperature,precipitation and frost days were dependent on temperature and precipitation; temperature's effect is greater than precipitation's;and a continuous increase in temperature is the main reason for changes in all other climatic factors,except precipitation.