The high sedimentation rate in the northern slope of the South China Sea (SCS),provides excellent materials for the study of sub-orbital climate changes. In this paper, we study benthic foraminifera from Core MD12-3429 (20°08. 52'N, 115° 49. 84' E),which is located in the upper northern slope of the South China Sea. Using the coarse fraction, abundance of benthic foraminifera (Cibicidoides wuellerstorfi, Uvigernia, Bulimina, Chilostomella oolina and Globobulimina pacifica ), and benthic foraminifera accumulation rate (BFAR),surface primary productivity and the seawater dissolved oxygen content are reconstructed since the Marine Isotope Stages 7 (MIS 7, about 243 ka BP) in the northern South China Sea. The primary productivity was higher during the interglacial and lower during the glacial corresponding to a poor oxygen during the interglacial and enriched oxygen during the glacial,which is mainly influenced by the East Asian monsoon and the surface ocean currents. The water depth of MD12-3429 is 903 m,within the intermediate transition zone of the South China Sea. So the bottom water at Site MD12-3429 reflects the property of the intermediate water of the northern South China Sea since the MIS7.