The Last Deglaciation is a period that global climate and environment altered largely. During the Last Deglaciation,a series of abrupt climate changes occurred in different ways and different regions of the world. A review of paleoclimatic evolution recorded by lacustrine sediments from the arid regions of high altitude and cold temperature on Qinghai-Tibetan Plateau,the arid regions of Northwestern China, the humid regions on Yunnan-Guizhou Plateau and the plains of Eastern China since Last Deglaciation were presented. The driving mechanism for climate changes is also discussed. The author proposes that future work should conducted to:1) enhancing the study of high-resolution time series of climatic evolution recorded by lacustrine sediments,2) promoting the comparative study of interdisciplinarity and other geologic records,3) strengthening the study of the Quaternary lake database in China and global climate changes,and 4) strengthening the tracer study of vapor sources.