Change-point detection of profiles has been a hot topic in quality management. Most of the literatures focus on the global change detection while research on local change problem is relatively few, and the ones that find change time as well as change area are extremely less. To solve local change problem,our paper proposes a method based on wavelet transform and cluster method. In this paper, we do a performance evaluation using Matlab and compare its result with WANOVA method. It shows that our method can detect change-point and locate change area under smaller difference between profiles.