Based on the collection of meteorological and natural disaster data in Nanning,Qinzhou and Longzhou of Beibu Gulf area of Guangxi,the effects of ENSO events on climate is studied. Statistical analysis of the relationships between the climate factors (precipitation,temperature,etc.) and the ENSO events clearly showed that the growth rate of annual average precipitation had a downward,the drop rate was 4. 08 mm·10a - 1,less than the national annual average precipitation decline rate (12. 69mm·10a - 1) since 1953; the growth rate of the annual average temperature was 0. 14 ℃·10a - 1,less than the national annual average temperature growth rate (0. 22 ℃ ·10a - 1). The annual average precipitation was decreased and the annual average temperature was increased in warm events happened years. The average annual precipitation was 1550. 6 mm and the average annual temperature was 22. 2 ℃. Compared to the normal years,the annual average precipitation was decreased at 24. 4 mm,the annual average temperature was increased at 0. 2 ℃. While in cold events happened years,the average annual precipitation was 1591. 3 mm and the average annual temperature was 21. 9 ℃. Compared to the normal years,the annual average precipitation was decreased at 16. 3 mm,the annual average temperature was increased at 0. 1 ℃. There was a significant correlation between the ENSO events and the regional drought and flood disasters,especially in the years of successional ENSO events.