Based on the comparative analysis between the simulation data from the high-resolution regional climate model (CCLM) and the CN05.1 data based on the observation in the reference period (1961-2005), we conducted projections on future climate change under the scenario of RCP4.5 at both annual and seasonal scales for the Hubei Province. The results showed: (1)CCLM presented a satisfactory simulation performance on the changing trend of temperature and its spatial distribution pattern, but was not matched very well with the CN05.1 observation precipitation data. (2)Under the RCP4.5, from 2006 to 2050,T, T_(min) and T_(max) in Hubei Province show a rising trend. The temperature is projected to be rising in all four seasons, while the winter has the fastest increase and the greatest contribution to the rise of annual T, T_(min) as well as T_(max) (3)Under the RCP4.5, in the period of 2006-2050, T, T_(min) and T_(max) will increase in the whole region compared to the reference period. The region with the high increase of temperature is located in the northern part of Hubei section of Han River. In spring, the regions with high increase of temperature are located in northwestern mountain area. In summer, the increase of T, T_(min) and T_(max) in the middle plain region is higher than other regions. In fall, the increase of T and T_(max) in southwestern mountain region is higher than that in other regions. The regions with high increase of T_(min) are located in the northern part of Hubei section of Han River. In winter, the increase of T in hilly regions of southeastern Hubei is higher than that in other regions, the same for the T_(min) in north part of north section of Han River and T_(max) in southwestern mountain region.