It is an inevitable stage of hepatic fibrosis in the development of chronic hepatopathy to hepatocirrhosis. Chinese medicine treatment has a better comprehensive curative effect in the reversal of liver fibrosis and early liver cirrhosis. Doctrine on yunqi is one of the most important basic theories of traditional Chinese medicine (TCM), it is a copy of precious medical legacy for the ancients to conjecture the climatic change, predict the vicissitude of many diseases and guide for disease diagnosis and treatment nursing. According to clinical practice for years, it has a positive meaning and important influence on liver fibrosis in diagnosis, treatment and health care of TCM. This article had a discussion on the characteristics of yunqi in Dingyou year and liver fibrosis, exploring the pathogenesis of liver fibrosis, Dingyou year clinical manifestation, treatment, selection of drugs and health care, and so on, in order to provide reference for comprehensive prevention and treatment for liver fibrosis in Dingyou year.