The increasing extreme climate events at the global scale are causing a series of scientific and societal issues under the background of global warming. The variations of daily temperature and precipitation of Gulang River basin in eastern Qilian Mountains showed that increasing frequency and amplitude of growing season length ( GSL) ,summer days ( SU25) and consecutive warm days ( CWD) as well as prominent warming indicated the good response to global warming. The quasi-3-year and quasi-8-year periodicities of precipitation in whole basin were identified by wavelet analysis. Extreme wet day precipitation ( R95P) is becoming more contribution for annual precipitation,but the simple daily intensity index ( SDII) presented regional diversity. The consecutive dry days ( CDD) revealed that humidification is going prominent. This work provided the science and technology support to water source and ecological services in Gulang River basin.