The cryosphere is the most direct and most sensitive spheres in climate system. In the context of global change,the interaction cryospheric changes with biosphere,lithosphere,hydrosphere,atmosphere and anthroposphere increasingly intensified. Especially,the rapid cryosphere changes had also a wide-ranging and profound negative impact on economic and social systems,and even endangered human well-being,and the healthy,harmonious and sustainable development of economic and social systems. Taking into account the geographical disadvantage of cryosphere and its relatively backward economic level,its ability to cope with or resist cryosphere changes is extremely limited. Currently,the adaptation is still the main way to tackle climate change impacts on cryosphere. The analysis of integrated impacts of cryosphere on economic and social system is the basis to adapt to the rapid change of cryosphere,and its adaptive management strategy is the ultimate goal to mitigate the adverse effects of rapid cryosphere changes and reduce the vulnerability for defending the adverse effects from natural, economic and social system.