In the past 150 thousand years, the earth experienced a complete glacial-interglacial cycle encompassing some special periods, such as the Marine Isotope Stage (MIS) 3 and Last Glacial Maximum (LGM). However, there have, to date, been few studies covering the full glacial-interglacial cycle, especially for the lake studies. Here we present a preliminary study from three inland lakes in Xinjiang, Northwest China, including Wulungu Lake, Bosten Lake, and Balikun Lake. A 24.11 m drilling core(WLG11E) was collected form the center of Wulungu Lake(47°14.4'N,87°13.1'E;479 m a.s.l.) in February 2011. The present study focuses on the top 9 m of the core. The age-depth model of the core was established based on seven AMS 14C dates measured by Beta Analytic Inc. USA and the Key Laboratory of Western China's Environmental Systems(Ministry of Education),Lanzhou University. A 51.6m long sediment core (BST12B)was taken from the center of Bosten Lake(42°0.7'N,87°9.3'E; 1051 m a.s.l.)in 2012. In this study, we focus on the depth interval of 0 ~20 m to infer climate changes. And twelve luminescence dating samples were used to establish the chronology based on multi-grain quartz OSL and K-feldspar post-IRIRSL(pIRIR290) dating. A 62.53 m long sediment core(BLK11 A) was retrieved from the center of Balikun Lake(43°36'~43°45'N , 92°42'~92°54'E; 1575 m a.s.l.) in June 2011. In this paper, we focus on the top 45 m of the core. The chronology framework of the core was established based on fourteen AMS 14C dates measured by Beta Analytic Inc. USA, one OSL date by the Key Laboratory of Western China's Environmental Systems (Ministry of Education),Lanzhou University and existed palaeomagnetic analysis. In this paper, we use lithology characteristics and grain-size data from these three lakes mentioned above to infer climate changes of Xinjiang since the Last Interglaciation. The results show that (1) Balikun Lake has continuous Late Pleistocene deposits spanning the last glacial-interglacial interval, thus is beneficial for the reconstruction of the past climate change in arid areas of China ; while the other two lakes are characteristic of haitus due to erosion. (2) After comparisons with these three records, we get the conclusion that : an optimum climate prevailed the most areas of Western China during MIS 5,and this humid condition made clay-dominated sedimentation in most lakes ; a continuous and gradually drying climate was found during MIS 3,leading to an increase in coarse particles in Balikun and Wulungu lakes. Hiatus occurred during LGM,accompanying with elevated grain size that indicated a degraded environment. The Holocene deposits were featured by clay and/or siltyclay, which suggested a gradual trend towards a wetter environment with high lake level.