The interdecadal and regional differences of temperature and precipitation are one of the important contents of global climate change research.In this paper,the seasonal and regional characteristics of temperature and precipitation variation in East Asia and North America were analyzed by using the CRU TS3.20 data from the Climatic Research Unit (CRU) of the University of East Anglia during the period of 1901-2014.Furthermore,we also analyzed the interannual variation of the area ratio that affected by extreme weather events in East Asia and North America by using the ERA-Interim data from the European Centre for Medium-Range Weather Forecasts (ECMWF) during the period of 1979-2015.It is found that the warming trend in East Asia [0.134 ℃·(10a)~(-1)] is higher than that in North America [0.102 ℃·(10a)~(-1)]over the past 110 years.The warming trend of arid and semi-arid regions in East Asia is slightly lower than that in East Asia,while the warming trend of arid and semi-arid regions in North America is slightly higher than that in North America.As for seasonal characteristics,the warming trend is obvious in the cold season.It is 2.9 (1.3) times higher in East Asia (North America) during cold season than during warm season.There is a significant latitude difference in seasonal warming trend.The warming rate for high latitude (45°N) region in East Asia and North America is generally greater during cold season than during warm season.The East Asia and North America have a greater increase in precipitation than Northern Hemisphere.The increase of precipitation is obvious during warm season and mainly occurs in the high latitudes of East Asia and North America (45°N).The increase of precipitation is not obvious for arid and semi-arid regions in East Asia [0.04 mm·(10a)~(-1)]and North America [0.07 mm·(10a)~(-1)].In East Asia and North America as well as arid and semi-arid regions,the area affected by extreme high temperature has an increasing trend,while the variation of the area affected by extreme low temperature is not obvious,and the area affected by extreme precipitation has a decreasing trend.The monthly average temperature in North American and East Asia and the arid and semiarid regions is more responsive to PDO (Pacific Decadal Oscillation) than that to ENSO (El Nino Southern Oscillation),and the monthly average precipitation has a stronger response to ENSO than PDO.