As one of the three human factors that affect climate change,real vegetation cover over the ecotone of agriculture and animal husbandry can affect regional and global climate by changing surface radiative forcing,energy and water circulation,greenhouse gas and aerosol emissions.The ecotone of agriculture and animal husbandry in China is a key area in China's land surface change.The regional climate effect caused by its evolution has important research significance.The impact of real vegetation cover over the ecotone of agriculture and animal husbandry changing in typical years on the regional climate over China during 2001-2010 was studied by using WRF (Weather Research and Forecasting) model and the surface classification data of satellite remote sensing in the years 1981 and 1990.There are some conclusions after analyzing the change of temperature,precipitation and wind.The main conclusions are as follows:(1) In 1990,compared with 1981,vegetation cover over the ecotone of agriculture and animal husbandry increases (decreases) in the north of 38° N,and the surface roughness increases(decreases).(2) When the vegetation cover over the ecotone of agriculture and animal husbandry increases (decreases) and the surface roughness increases (decreases),the temperature of the agriculture and animal husbandry and the nearby areas increases (decreases).(3) The evolution of vegetation cover over the ecotone of agriculture and animal husbandry leads to the " positive-negative-positive" of the precipitation difference over China from the east to the west.The surface roughness increases (decreases) causes the precipitation increases (decreases).When there are more precipitation,there will be more water cycle.The evolution of vegetation cover over the ecotone of agriculture and animal husbandry are more sensitive to places where precipitation is high.The more precipitation with more water circulation causes the more prominent the effect of vegetation evolution on precipitation.(4) The vegetation evolution of the intersected zone mainly affects the middle and high-level circulation fields,the cyclonic (anti-cyclonic) circulation at 500 hPa corresponds well with the increase (decrease) of the precipitation difference field.