The research on the influence of climate change on air pollution is helpful to deepen understanding of the formation mechanism of air pollution. Based on comprehensive observations of complex atmospheric pollutions and meteorology from 1996 to 2015,the influence of climatic change on air pollution was investigated in Zhejiang Province. The results showed the obvious climatic changes of more frequent high-pressure weather,the increase of temperature as well as precipitation concentration,and even the decrease of net radiation,sunshine duration,wind speed,daily temperature range and evaporation capacity were found. The climatic change caused the decline of the capacity of atmospheric diffusion. The annual average atmospheric diffusion coefficients descend to 0.55 and 0.81 that the descent percentages are nearly 35.71% and 42.69% in Hangzhou City and Zhejiang Province,respectively. The atmospheric diffusion index presents the strong inverse correlation with the concentrations of PM_(10),PM_(2.5) and annual haze day,and the concentrations of PM_(10),PM_(2.5) as well as annual haze day presents decreasing trend with the atmospheric diffusion index increasing and vice verse. The correlation coefficients between the atmospheric diffusion index and concentrations of PM_(10),PM_(2.5) are 0.73 and 0.76 in Hangzhou City,respectively. The correlation coefficients between the atmospheric diffusion index and annual haze day are 0.77 and 0.78 in Hangzhou City and Zhejiang Province, respectively,and T-values in test are 28.88 and 30.81. The result illustrates the capacity of atmospheric diffusion induced by climatic change is an important influence factor of atmospheric pollution,but the different pollutants are differently affected by climatic change. The key climatic elements are precipitation,wind speed and relative humidity influenced on PM_(10) concentration,and then atmospheric radiation,air temperature as well as precipitation on PM_(2.5) concentration. The most important climatic element on SO_2 and SO_4~(2-) concentration is air temperature. Different from sulfide,the most significant climatic element on NO_2,NO_3~- and NH_4~+ concentration is atmospheric radiation. On the whole,climatic change in Zhejiang Province in recent 20 years may be benefit to the concentration increases of PM_(10),PM_(2.5),NO_2 and O_3 as well as the concentration decreases of SO_2,NO_3~-,SO_4~(2-) and NH_4~+.