Sulfate and BC aerosol are important but opposite driving factors to global climate change. A modified WRF/Chem model and 2010 EDGAR/HTAP V2 inventory were used to simulate the sulfate and BC formation and distribution over East Asia in 2010. The study showed that the turnover time of sulfur was calculated to be 4.04 d and sulfur was removed mainly by wet deposition, mainly as sulfate. China was a net exporter of sulfur and black carbon in East Asia, and the remaining four countries were net importers. The peak sulfate column concentration and BC column concentration were found to occur in Central China, while the minimum sulfate column concentration and BC column concentration occurred in Mongolia. Obvious eastward overspill effect of sulfate was showed, especially in spring and winter. Modeled sulfate column concentration in summer was higher than that in spring, autumn and winter, mainly due to high oxidation rate and in-cloud oxidation rates Kw in summer. Modeled BC column concentration in spring was the highest, which was not only related to anthropogenic emissions, but also related to biomass burning emissions.