The environment in Hetian river basin is fragile.The runoff is extremely vulnerable to climate changes.Through the analysis of data from 1980 to 2013,we found that the annual precipitation at Tong Gu Zi Lu Ke station showed a significant increasing trend at a rate of 18 mm/(10 a).The annual average temperature was increasing by 0.232℃/(10 a).The highest temperature appeared in 2007;the lowest temperature appeared in 2012.The annual sunshine hours were decreasing at a rate of 21.5W/(m~2·(10 a)).The annual runoff was increasing at a rate of 23.5*10~7 m~3/(10 a).The runoff had a stronger correlation with antecedent temperature than precipitation.