Based on a questionnaire survey of corporate managers on climate change in North China, Pearl River Delta, Hunan and Hubei provinces from 2012 to 2015, two first level indices were constructed: climate change awareness index and index of business responses to climate change. Through the descriptive statistics of the survey results and the contingency table analysis, the following conclusions are conducted: the climate change awareness index is at a general level and is significantly affected by age, industry type and business type; index of business response to climate change is also at a general level and there is a large gap between different respondents, and climate change awareness level, future expectations and independent intellectual property ownership have significant influences on it.