Vegetation is the main component in the ecosystem which is the link point among pedosphere,atmosphere and biosphere,the vegetation distribution changes of time and space affects the earth material cycle,including water,carbon and others, and energy cycle such as light and heat. Based on the remote sensing data and meteorological data,and remote sensing image processing platform and ArcGIS software,the normalized vegetation index of Guangxi region was extracted from 2007 to 2016. The vegetation change trend was analyzed using a linear regression method and partial correlation method. The results showed that: NDVI value of Guangxi vegetation was between 0.78-0.82 from 2007 to 2016 presenting a rise trend,high vegetation coverage area was the largest and low vegetation coverage area was the smallest. Karst area vegetation cover has improved that the improved area of vegetation cover was more than the degrade area,the vegetation cover degree of variation in Karst and non-Karst area was given priority to stability. Vegetation NDVI was partial correlation with precipitation,temperature and minus partial correlation,negative partial correlation area was greater than the positive correlation.