Through selecting four typical weather of Yarkant River basin and the monthly data observed from hydrometric station, this paper makes a contrastive analysis of the evolution characteristics of air temperature, rainfall, and runoff of Yarkant River basin against the background of climate change, and explores the influence of climate change on hydrological extremes. The results are as follows. (1)During climate change, there was an overall trend towards warming and humidification in almost 55 a of Yarkant River basin, among which the climate change in 1998 was the most prominent. As for the four typical observation stations, the station of Kuluklangan witnessed the biggest change in air temperature and rainfall (0.24 ℃·10 a~(- 1), 7.41 mm·10 a~(- 1)). (2) The runoff variation was increased linearly on the whole and saw a significant change within the year. Among which the highest runoff volumes of Yarkant river and Tizinafu river were respectively concentrated in July and August. (3)There was a remarkably growing trend in terms of the number of hydrological extremes in almost 55 a of Yarkant River basin, and the runoff change in June witnessed the biggest change. The increasing of precipitation and the accelerating melt of glacier was the leading factors of the frequent occurrences of hydrological extremes. Therefore, we should improve the solutions of hydrological events to climate change and strengthen the impact evaluation over flood damage, which is of great importance to increasing the use efficiency of the water resource of Yarkant River basin and decreasing the negative effect of climate change on it.