In view of the impact of global climate warming,the annual average temperature along the Qinghai Tibet Railway is rising year by year.Based on the meteorological and ground temperature monitoring data over the years in different regions along the Qinghai-Tibet Railway,the evolution of climatic factors and the response of permafrost to global climate change in the engineering corridor of Qinghai-Tibet Railway are studied.Results show that the temperature in the engineering corridor of the Qinghai Tibet Railway rises by an average of 0.03℃.The annual precipitation is mostly between 250~ 450mm,and the trend of fluctuation increases.The freezing index and melting index are increasing year by year,and the warm winter phenomenon is obvious.The increase rate of ground temperature reaches 0.06℃·a-1,which is 1.34times of temperature rising rate.From 2007to 2013,the uplift in the natural upper limit of the permafrost regions along the line accounted for only 9% ,while the decline in natural upper limit accounted for 91% .The ground temperatures at different depths of foundation permafrost are increasing.The ground temperature rising rate near the upper limit is generally the maximum.The permafrost degradation is mainly from top to bottom.The permafrost degradation in the north of Tanggula Mountain is more obvious than that in the south of Tanggula Mountain.