Based on the analysis of elementary characteristics of wave velocities of soils at the permafrost sites along Qinghai-Tibet Engineering Corridor,combining the results of dynamic triaxial test,using three time histories of ground motion acceleration with different exceedance probabilities related to the research area,the characteristics of ground motion are analyzed to estimate the amplification effects of permafrost areas,as well as the seismic response of frozen soil ground. Considering the influence of the global warming and engineering activities,the change of the active layer and the variety of permafrost thickness are taken into account in the numerical calculation. The research results show that the influence of the active layer thickness is not significant despite the ground peak acceleration increases with active layer thickness,the changes of the active layer are not enough to alter the inherent characteristics of permafrost sites,the active layer thickness has little influence on the characteristic site period.The results also indicate that the permafrost thickness has an obvious influence on the site effect and the sites with large permafrost thickness have no amplification effect on the ground motion.The inhibitory effects are more obvious with higher intensity of the input ground motion.The permafrost thickness has a significant impact on the characteristic site period.The characteristic site period gradually increases with the increase of the permafrost thickness,showing a logarithmic relationship.