In order to evaluate of the difference in the impact of climate changes on phenology of winter wheat due to regions,we analyzed the spatial-temporal changes of key growth stage of winter wheat in Huang-Huai-Hai Plain(HHHP),Loess Plateau(LP) and Northwest of China(NWC) using 57 agricultural-climate station data from 1992 to 2013,which were obtained from China Meteorological Administration. The results indicated that the turning-green and maturity period of winter wheat were generally delayed from 1992 to 2013 in the north of China. In addition,the range of changes in key growth periods of winter wheat was increased gradually from west to east,in another word,from NWC to HHHP,whereas,the differences were not dramatically obvious. The average temperature and minimum temperature are the main meteorological factors affecting the turning-green and maturity periods of winter wheat in HHHP,respectively,while the changes of key growth stages of winter wheat in LP are mainly affected by the changes of the average temperature. However,in the NWC,the turning-green period has a significantly negative correlation with the minimum temperature,while the time of maturity period is mainly affected by the change of average temperature in NWC region. In addition,the effects of sunshine,monthly temperature range,and precipitation on the key growth period of wheat are contrasting in the HHHP/LP area and the northwest inner area. In the HHHP and LP regions,the changes in sunshine duration and monthly temperature range have a positive correlation with turning-green and maturity of winter wheat and precipitation was negatively correlated with the two phenology parameters. However,the relationship between sunshine duration and monthly temperature range and phenology of winter wheat is negative in NWC,while precipitation has a positively relationship with turning-green and maturity periods in this region,which is contrasting with the correlation between the parameters in HHHP and LP. It is suggested that the increased precipitation is favorable for the growth of winter wheat which can prolong crop growth in this arid area.